Serum spexin, adiponectin and leptin levels in polycystic ovarian syndrome in association with FTO gene polymorphism

Association between circulating adiponectin levels and polycystic ovarian syndrome

BACKGROUND Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in younger and lean patients are limited. Therefore, the aim of the present stud...

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

Association of Adiponectin rs1501299 Gene Polymorphism with Adiponectin Levels and Type 2 Diabetes in an Iranian Population

Background and Objectives: Adiponectin is an adipokine, which is abundantly expressed in adipose tissue and has a potent roles in insulin sensitivity. This study aimed to test the association of single nucleotide polymorphism of rs1501299 of the adiponectin gene with adiponectin levels and type 2 diabetes.   Methods: This case-control study was conducted on 80 diabetic patients with fasting bl...

Association between adipose tissue expression and serum levels of leptin and adiponectin in women with polycystic ovary syndrome.

We reviewed emerging evidence linking serum levels and adipose tissue expression of leptin and adiponectin in women with polycystic ovary syndrome (PCOS). Previous data obtained by our group from a sample of overweight/obese PCOS women and a control sample of normal weight controls, both stratified by BMI, were reanalyzed. Circulating levels of leptin and adiponectin were determined by commerci...

Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome